Core Health Diagnostics | Peptides
Peptides — the body’s own signals, amplified
Short-chain amino acids that tell your biology exactly what to do
Peptides are short chains of amino acids — the same building blocks that make up proteins — but in small, targeted sequences of typically 2 to 50 amino acids. The human body produces hundreds of peptides naturally; they act as signalling molecules, carrying precise instructions between cells, organs, and systems. Therapeutic peptides replicate or amplify these natural signals — directing the body to produce more growth hormone, repair damaged tissue, reduce inflammation, or optimise specific metabolic functions.
Because peptides are structurally identical to signals the body already makes, they work with the body rather than forcing it — producing physiological effects that are natural in mechanism, targeted in scope, and generally well-tolerated.
01 · Fat Loss & Body Sculpting
Fat Loss & Body Sculpting
Metabolic peptides work by targeting the biological pathways that govern fat storage, fat burning, insulin sensitivity, and energy utilisation — producing fat loss that preserves muscle and reshapes body composition at the cellular level.
AOD-9604
The intelligent fat-burning fragment
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A modified fragment of human growth hormone (hGH) specifically selected for its ability to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat creation) — without the blood sugar or growth-promoting effects of full hGH. AOD-9604 targets stubborn fat deposits directly, particularly in the abdominal region, while preserving lean muscle mass. It simultaneously improves metabolic efficiency and insulin sensitivity, meaning the body becomes better at using energy from food rather than storing it as fat.
Tesamorelin
Deep visceral fat elimination
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A synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce more growth hormone — specifically studied and clinically validated for the reduction of visceral fat, the metabolically dangerous fat that accumulates around the internal organs in the abdominal cavity. Visceral fat cannot be seen from the outside and does not respond well to diet alone. Tesamorelin produces clear, measurable reductions in this deep fat layer, improving body shape and significantly reducing the cardiovascular, metabolic, and inflammatory risks associated with high visceral fat levels.
MOTS-c
Energy from inside the cell
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A mitochondrial-derived peptide — one of the very few peptides encoded not by the nuclear genome but by mitochondrial DNA itself. MOTS-c functions as a metabolic regulator that improves mitochondrial efficiency (the primary cellular energy-producing organelle), enhances fat oxidation, and improves insulin sensitivity by activating AMPK, the enzyme that acts as the cell’s energy sensor. The result is improved daily energy, better fat utilisation, and a more responsive metabolism — all driven from within the cell rather than through external hormonal stimulation.
Humanin
Advanced cellular protection from within
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Another mitochondrial peptide with a broad protective profile. Humanin improves insulin sensitivity and glucose regulation, supports metabolism and fat burning, and offers neuroprotection — protecting brain cells from the damage associated with oxidative stress, beta-amyloid accumulation (relevant in Alzheimer’s disease research), and metabolic dysfunction. Humanin levels naturally decline with age, making it particularly relevant in anti-ageing and longevity medicine. It promotes overall cellular stability and energy balance from the inside out.
Clinical pairing: AOD-9604 and Tesamorelin are often used together in body recomposition protocols — AOD-9604 targeting stubborn subcutaneous fat while Tesamorelin addresses the deeper visceral layer. MOTS-c and Humanin are added in anti-ageing protocols where metabolic efficiency and cellular protection are the primary goals alongside fat reduction.
02. Strength, Muscle & Recovery
Muscle, Strength & Accelerated Recovery
Performance and recovery peptides work at the tissue, cellular, and growth factor level — accelerating the repair of muscle, tendons, ligaments, and joints while stimulating the biological mechanisms that drive muscle growth and strength development.
BPC-157
Body Protection Compound — the master healer
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Derived from a protein found naturally in gastric juice, BPC-157 (Body Protection Compound-157) has an extraordinarily broad tissue repair profile. It significantly accelerates the healing of muscles, tendons, ligaments, and joints — documented in animal research at a rate measurably faster than standard recovery. It also reduces chronic inflammation, supports gut health (improving conditions from gastric ulcers to inflammatory bowel disease), and enhances the process of tissue regeneration and cellular renewal. BPC-157 is one of the most researched regenerative peptides available, with a well-established safety profile in the literature.
BPC-157 + TB-4 / TB-500
The most powerful tissue repair combination
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When BPC-157 is combined with Thymosin Beta-4 (TB-4, also known as TB-500), the two peptides work synergistically — producing faster and deeper tissue repair than either achieves alone. BPC-157 initiates local tissue repair at the injury site, while TB-4/TB-500 works systemically through actin regulation, reducing inflammation across a wider area and supporting whole-body healing and immune modulation simultaneously. This combination is particularly effective for complex or slow-healing injuries, post-surgical recovery, and for patients with multiple sites of musculoskeletal damage.
IGF-1 LR3
Advanced muscle performance and cell renewal
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Insulin-Like Growth Factor 1 (IGF-1 LR3) is a modified, extended-half-life analogue of the body’s natural IGF-1 — the primary mediator of growth hormone’s anabolic effects at the muscle level. IGF-1 LR3 significantly enhances muscle cell growth by stimulating satellite cell activation (the precursor cells that build new muscle tissue), increases post-exercise recovery speed, supports the breakdown of fat for energy, and participates in cellular renewal processes. It is administered immediately post-exercise to capitalise on the anabolic window when muscle cells are most receptive to growth signals.
MGF
Mechano Growth Factor — the post-exercise amplifier
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Mechano Growth Factor (MGF) is a splice variant of IGF-1 that is naturally produced in muscle tissue in response to mechanical stress (exercise). Where IGF-1 LR3 acts systemically, MGF acts locally at the site of muscle stress — activating dormant satellite cells immediately and signalling them to proliferate and differentiate into mature muscle fibre. The net effect is enhanced muscle growth, strength development, and recovery — particularly notable in training windows where progress has plateaued. MGF is used post-exercise and pairs effectively with IGF-1 LR3 for maximum anabolic signalling.
03 · Focus, Cognition & Mental Balance
Cognitive Performance & Mental Wellbeing
Nootropic and anxiolytic peptides act on the brain’s own neuropeptide systems — improving neurotransmitter balance, reducing stress hormone activity, enhancing BDNF (Brain-Derived Neurotrophic Factor) production, and improving focus and memory without the side effects or dependency risks of conventional pharmaceutical options.
Semax
Mental clarity and cognitive amplification
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Semax is a synthetic peptide analogue of ACTH (adrenocorticotropic hormone) developed in Russia, where it has been used clinically for cognitive enhancement and neurological conditions since the 1980s. It works primarily by increasing Brain-Derived Neurotrophic Factor (BDNF) — the protein responsible for the growth, maintenance, and plasticity of neurons — and by enhancing serotonin and dopaminergic neurotransmission. The clinical results include improved focus, sharper working memory, reduced brain fog, and significantly enhanced cognitive performance during both short-term and sustained use. Patients with Long COVID-related cognitive impairment and chronic fatigue report notable improvements with Semax protocols.
Selank
Psychological calm without sedation
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Selank is a synthetic anxiolytic peptide developed by the Russian Academy of Sciences — a heptapeptide analogue of tuftsin with significant anxiolytic (anti-anxiety) properties and a favourable safety profile compared to benzodiazepines. Selank modulates the GABAergic system (the brain’s primary inhibitory system) and enhances BDNF expression, simultaneously improving mood, reducing anxiety, and supporting concentration. Unlike pharmaceutical anxiolytics, Selank does not produce sedation, impaired cognition, or dependency. It restores psychological calm while maintaining or improving mental clarity — making it suitable for patients managing chronic stress, generalised anxiety, or anxiety-related cognitive impairment.
DSIP
Delta Sleep-Inducing Peptide — natural sleep and stress modulation
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Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide with sedative and stress-modulating properties that extends beyond sleep into broader neuroendocrine regulation. DSIP promotes the onset and depth of deep (delta-wave) sleep — the restorative phase critical for growth hormone secretion, tissue repair, immune function, and cognitive consolidation — without the dependency and rebound insomnia associated with conventional sleep medications. It also reduces cortisol and stress hormone levels. It is frequently combined with CJC-1295 and Ipamorelin in sleep and growth hormone optimisation protocols to amplify both sleep quality and nocturnal GH release simultaneously.
04 · Sleep Quality & Growth Hormone Optimisation
Deep Sleep & Natural Growth Hormone
Growth hormone secretagogue peptides stimulate the pituitary gland to produce more of the body’s own growth hormone naturally — improving sleep quality, body composition, recovery, and the full spectrum of GH-dependent biological functions without the risks associated with exogenous GH administration.
CJC-1295
Sustained growth hormone release — youthful restoration
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CJC-1295 is a synthetic analogue of Growth Hormone-Releasing Hormone (GHRH) with a significantly extended half-life compared to natural GHRH — stimulating the pituitary gland to release growth hormone in a sustained, physiological pulsatile pattern that mimics the body’s natural nocturnal GH secretion. The clinical effects of restored GH levels are broad: reduced fat (particularly visceral), increased lean muscle, improved deep sleep quality, better energy and recovery, improved skin and connective tissue quality, and enhanced overall sense of vitality. CJC-1295 restores hormonal balance safely and is particularly valuable for patients over 35 whose natural GH production has begun to decline significantly.
Ipamorelin
Selective, clean GH stimulation
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Ipamorelin is a selective growth hormone secretagogue — a synthetic peptide that stimulates GH release from the pituitary by mimicking ghrelin (the GH-stimulating hormone) at the ghrelin receptor. It is highly selective: it stimulates GH release without significantly elevating cortisol or prolactin, unlike some older GH secretagogues. This clean selectivity makes it one of the safest and most widely used GH peptides in clinical practice. It improves deep sleep quality (GH is secreted primarily in the first hours of deep sleep), supports fat loss, increases lean muscle, and enhances daily energy. Its effects complement CJC-1295 strongly and the two are frequently combined.
CJC-1295 + Ipamorelin + DSIP
The complete sleep and recovery protocol
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This triple combination is the most comprehensive sleep and growth hormone optimisation protocol available in peptide therapy. CJC-1295 provides the GHRH signal; Ipamorelin provides the ghrelin signal — together they produce a synergistic, amplified GH pulse that exceeds either peptide alone. DSIP is added to deepen the sleep cycle in which this GH release occurs, maximising the nocturnal GH secretion window and the tissue repair, fat metabolism, and immune restoration that happens during deep sleep. The net effect: deeper, more restorative sleep, higher nocturnal GH output, improved body composition, faster recovery, and better hormonal balance — all working simultaneously.
Sermorelin
The natural GH alternative — safe and effective
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Sermorelin is a synthetic version of the first 29 amino acids of natural GHRH — the minimum active fragment required to stimulate GH release from the pituitary. It is the oldest and most extensively studied GHRH analogue and is considered a safe, physiological approach to GH stimulation because it works through the body’s own regulatory system, preserving the natural feedback inhibition that prevents excessive GH levels. Sermorelin is particularly used for GH restoration in patients who prefer a well-established, conservative protocol or who are beginning peptide therapy for the first time. It improves body composition, energy, sleep quality, and recovery.
05 · Beauty, Skin & Hair
Skin Radiance, Hair Growth & Cellular Beauty
Beauty peptides work from the inside out — stimulating the skin’s own fibroblasts to produce more collagen and elastin, improving tissue repair, reducing inflammation, and promoting hair follicle health through biological signalling rather than topical application.
GHK-Cu
Copper peptide — nature’s regeneration signal
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GHK-Cu (Glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper peptide found throughout the human body that plays a key role in tissue repair, collagen production, and skin regeneration. Levels decline significantly with age. Therapeutically, GHK-Cu activates fibroblasts to produce new collagen and elastin, reduces skin inflammation, improves wound healing and scar remodelling, and stimulates hair follicle activity — increasing follicle size and prolonging the growth phase. It is one of the most evidence-backed cosmetic and regenerative peptides available, with decades of published research confirming its effects on skin quality and hair growth.
GLOW Peptide
BPC-157 + Thymosin Beta + GHK-Cu — the inside-out beauty protocol
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GLOW is a curated combination peptide protocol specifically designed for comprehensive skin and hair rejuvenation. BPC-157 provides the foundational tissue repair and anti-inflammatory signalling; Thymosin Beta-4/TB-500 adds systemic wound healing support, angiogenesis (new blood vessel formation for better skin perfusion), and immune modulation; GHK-Cu delivers the targeted collagen stimulation and hair follicle activation. Together, the three work across multiple biological levels — reducing inflammation that accelerates skin ageing, improving tissue regeneration, stimulating structural protein synthesis, and optimising the biological environment for visible skin and hair improvement. A 4–8 week daily protocol produces progressive, cumulative results.
KLOW Peptide
BPC-157 + TB-500 + GHK-Cu + KPV — comprehensive gut, immune & skin support
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KLOW adds KPV (a tripeptide fragment of alpha-MSH with potent anti-inflammatory properties) to the BPC-157, TB-500, and GHK-Cu combination — creating a broader protocol that addresses chronic inflammation systemically, supports gut mucosal health, modulates the immune response, and drives tissue repair across multiple systems simultaneously. KLOW is designed for patients who have both aesthetic goals and underlying inflammatory or gut conditions — where the skin presentation is often a surface reflection of deeper systemic inflammation. Treating the inflammation with KPV while stimulating repair with BPC-157 and GHK-Cu produces results neither approach achieves alone.
06 · Hormonal Health & Sexual Wellbeing
Hormonal Balance & Sexual Health
Hormonal peptides work within the body’s own neuroendocrine axis — stimulating natural hormone production, improving fertility hormones, and restoring sexual function through physiological mechanisms rather than hormone replacement.
PT-141 (Bremelanotide)
Central sexual arousal — for men and women
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PT-141 is a melanocortin receptor agonist that works centrally — in the brain — rather than on the vascular system like conventional erectile dysfunction medications. It activates melanocortin receptors in the hypothalamus, producing sexual arousal through the neurological pathway that the body uses naturally. This central mechanism means it is effective for both men and women, addressing low libido and hypoactive sexual desire disorder (HSDD) in women as well as erectile dysfunction in men. It works regardless of the physical cause of the dysfunction — making it valuable in cases where vascular or psychological factors both play a role. Results are typically noticeable within 1–2 hours of administration.
Kisspeptin
The fertility and hormonal axis activator
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Kisspeptin is a naturally occurring neuropeptide that acts as a key regulator of the hypothalamic-pituitary-gonadal (HPG) axis — the hormonal cascade that controls reproductive function in both men and women. By stimulating the release of GnRH (Gonadotropin-Releasing Hormone) and subsequently LH and FSH, Kisspeptin directly activates the body’s reproductive hormonal system. It is used therapeutically to support fertility (LH stimulation for ovulation in women; testosterone and sperm production support in men), and to restore hormonal balance in patients with hypothalamic amenorrhoea, low testosterone, or impaired fertility. A genuinely natural approach to reproductive hormonal support.
HCG (Human Chorionic Gonadotropin)
Effective hormonal testosterone support for men
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Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone that mimics Luteinising Hormone (LH) — the pituitary signal that tells the testes to produce testosterone. Therapeutically, hCG is used in men to stimulate and maintain natural testosterone production, support sperm production and male fertility, and preserve testicular function and size in patients on testosterone replacement therapy (where exogenous testosterone suppresses natural LH signalling). For men experiencing low testosterone with intact testicular function, hCG can restore natural testosterone production without the suppression associated with direct TRT. It is also used adjunctively with TRT to maintain testicular axis function during treatment.
07 · Cellular Energy & Longevity
Anti-Ageing & Cellular Rejuvenation
Longevity peptides work at the deepest biological level — within the mitochondria, at the telomere, and inside the cell’s core energy machinery — to slow the biological processes of ageing, restore cellular vitality, and extend healthspan.
Epithalon
Telomerase activator — the longevity peptide
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Epithalon (Epitalon) is a tetrapeptide originally developed by the St. Petersburg Institute of Bioregulation — the most studied peptide in anti-ageing science. Its primary mechanism is the activation of telomerase, the enzyme that maintains telomere length. Telomeres are the protective caps on chromosomes that shorten with each cell division; their progressive shortening is one of the primary biological mechanisms of cellular ageing. By reactivating telomerase, Epithalon slows or partially reverses this shortening — supporting cellular longevity, immune function, and sleep quality. It also regulates melatonin production through pineal gland support. The most commonly used dosing schedule involves periodic intensive courses rather than daily administration.
NAD+
The cellular battery recharge
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NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every cell of the body — central to energy metabolism, DNA repair, and the activity of sirtuins (the longevity-associated proteins regulated by caloric restriction and fasting). NAD+ levels decline significantly with age — falling by as much as 50% between age 40 and 60. This decline impairs mitochondrial energy production, reduces DNA repair capacity, and undermines the body’s ability to respond to cellular stress. Administered by injection, NAD+ rapidly restores intracellular levels — producing fast, noticeable improvements in energy, focus, and cognitive clarity, alongside the longer-term benefits of improved DNA repair and cellular resilience.
CJC-1295 / Ipamorelin
Complete body transformation — GH optimisation combined
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When CJC-1295 and Ipamorelin are combined (the most widely used GH peptide protocol), the GHRH signal and ghrelin signal synergise — producing amplified GH release that exceeds either peptide alone. This combination drives fat loss while preserving lean muscle, deepens sleep quality and restorative capacity, enhances daily energy, and supports the broad spectrum of anti-ageing effects associated with optimised GH levels — including improved skin quality, faster recovery, and better hormonal balance. It is the protocol of choice for patients seeking comprehensive body and performance improvement alongside anti-ageing benefits.
SS-31
Advanced mitochondrial energy therapy
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SS-31 (Elamipretide) is a cell-permeable peptide that selectively accumulates in the inner mitochondrial membrane — the site of ATP (energy) production. It stabilises cardiolipin, a lipid critical to the electron transport chain, preventing the structural disorganisation that accumulates with age and disease and that underlies mitochondrial dysfunction. SS-31 dramatically improves mitochondrial ATP output, reduces oxidative stress within the mitochondria, reduces fatigue, and enhances physical performance. It has been studied in heart failure, ischaemia-reperfusion injury, and age-related mitochondrial decline — making it one of the most mechanistically precise energy and longevity peptides available.
08 · Immunity & Inflammation Modulation
Immune Strength & Inflammation Control
Immunomodulatory peptides regulate immune function at the cellular level — strengthening appropriate immune responses, reducing chronic or excessive inflammation, and supporting tissue repair in conditions where the immune system is dysregulated.
Thymosin Alpha-1
The immune system’s master activator
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Thymosin Alpha-1 (Tα1) is a naturally occurring peptide produced by the thymus gland — the immune system’s primary educational organ. It is one of the most extensively studied and clinically used immunomodulatory peptides, approved in over 35 countries (under the brand name Zadaxin) for the treatment of hepatitis B, hepatitis C, and as an adjunct to cancer treatment. Tα1 enhances T-cell function (particularly helper T-cells and cytotoxic T-cells), activates Natural Killer cells, and modulates cytokine production — strengthening the immune system’s ability to identify and eliminate viruses, bacteria, and abnormal cells while reducing the dysregulated inflammation associated with autoimmune conditions and chronic infections.
Thymosin Beta (TB-4 / TB-500)
Tissue repair, wound healing, and immune modulation
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Thymosin Beta-4 (and its synthetic analogue TB-500) is a naturally occurring peptide with potent wound healing, anti-inflammatory, and tissue repair properties. Its primary mechanism involves actin regulation — TB-4 sequesters actin monomers, allowing the cytoskeleton to reorganise rapidly during injury response. It promotes angiogenesis (new blood vessel formation into damaged tissue), reduces scar formation, modulates inflammatory cytokines, and supports the migration of repair cells to the injury site. TB-500 (the synthetic version designed for greater systemic availability) is used particularly for injuries where improved blood supply and tissue matrix organisation are needed — and as a systemic complement to the local repair activity of BPC-157.
KPV
Targeted anti-inflammatory — gut, skin, and systemic
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KPV is a tripeptide fragment of alpha-melanocyte stimulating hormone (α-MSH) — specifically the C-terminal sequence responsible for its anti-inflammatory activity. It binds to melanocortin receptors in the gut, skin, and immune cells, directly reducing the production of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) at a local level. KPV is particularly effective for gut inflammation (IBS, IBD, Crohn’s, ulcerative colitis), inflammatory skin conditions (eczema, psoriasis, acne), and as part of broader systemic inflammation protocols. Its targeted, non-immunosuppressive mechanism makes it suitable for long-term use without the systemic side effects of steroid-based anti-inflammatory drugs.
Medical transparency — peptide therapy at Dr. Ozone Clinic
All peptide protocols at Dr. Ozone Clinic are prescribed and overseen by licensed physicians. Peptide therapy is a rapidly evolving area of medicine — the evidence base varies by peptide and indication, from highly studied (BPC-157, Thymosin Alpha-1, NAD+) to emerging clinical use (MOTS-c, SS-31). Peptides are not a cure-all and are not appropriate for everyone. Your physician will assess your clinical picture, goals, and relevant investigations before recommending any peptide protocol. All protocols are reviewed for compatibility with existing medications and conditions. No dosage information is provided on this page; all dosing is individually determined by your physician.
Peptide therapy works because it speaks
the language your biology already understands.
